Invest in Discovery. Change the Future of Brain Health.
Every Brain Tells a Story.
The Truth Lives in Human Tissue.
Diseases of the aging brain are among the greatest scientific and medical challenges of our time. We believe transformative discoveries begin with understanding patients, asking bold questions, and challenging established assumptions. By bringing together human neuropathology, experimental neuroscience, genetics, and artificial intelligence, we are uncovering new ways to understand Alzheimer's disease and related neurodegenerative disorders.
Our work occupies the precompetitive space of biomedical research, generating fundamental knowledge and shared scientific resources that benefit the entire research community, independent of any single commercial product or therapeutic strategy.
Philanthropy gives us the freedom to pursue unconventional ideas, preserve irreplaceable human brain collections, and train the next generation of scientists. Join us in building the foundations upon which future breakthroughs depend.
Why Human Brains Matter
Despite decades of progress, we still do not fully understand why Alzheimer's, Parkinson's, FTD, and related diseases develop, why they affect certain parts of the brain, or why patients experience them so differently.
These answers cannot come from experimental models alone. Human brain tissue provides an irreplaceable window into the biology of disease, connecting a patient's clinical journey with the cellular and molecular changes underlying it.
Every donated brain is an extraordinary gift, one that can support generations of scientific discovery.
What Makes Our Approach Different?
We bring together world-class neuropathology, large collaborative tissue collections, genetics, molecular biology, and artificial intelligence to investigate human brain disease from multiple perspectives.
Our mission is fundamentally precompetitive. We are not a drug-screening operation or a commercial development platform. We build the scientific foundations upon which future advances depend, creating knowledge, tools, and resources that empower researchers across institutions and disciplines.
From characterizing previously unrecognized diseases to building the 10,000 Brains Project, we believe that understanding patients, not simply modeling disease, is where discovery begins.
What Philanthropy Makes Possible
Philanthropy provides the flexibility to pursue important scientific questions that traditional funding mechanisms often overlook. Your support can help us:
Sustain the specialized scientists and technicians who preserve and study irreplaceable human tissue.
Train the next generation of neuropathologists and neuroscientists through research fellowships.
Digitize brain collections and develop shared AI and computational infrastructure.
Launch ambitious, unconventional research projects before they qualify for traditional grant funding.
Build enduring scientific resources that serve investigators around the world.
An investment in the Brain Bank is an investment in the foundations of discovery, not just a single experiment or outcome.
Our Scientific Impact
Our research has contributed to landmark discoveries in aging and neurodegeneration, including the characterization of primary age-related tauopathy (PART), advances in the understanding of tau biology, traumatic brain injury, and atypical parkinsonian disorders, and pioneering applications of artificial intelligence to human neuropathology.
Through national and international collaborations, we transform individual brain donations into shared scientific knowledge. Our impact extends beyond our own publications: every specimen preserved, dataset generated, and investigator supported creates opportunities for discoveries throughout the research community.
Above all, we honor the generosity of brain donors and their families by working to ensure that each donation has the greatest possible scientific impact.
Ways to Partner With Us
We welcome individuals, families, foundations, and institutional partners who share our commitment to advancing fundamental neuroscience.
Opportunities include direct gifts, named research funds, trainee fellowships, sponsorship of major initiatives such as the 10,000 Brains Project, contributions of equipment and computational resources, and endowed or legacy gifts.
Whether supporting an individual scientist or building a lasting scientific resource, your partnership helps preserve the independence, creativity, and collaborative spirit essential to transformative discovery.
Help us understand the human brain. Everything that comes next depends on it.
Frequently Asked Questions-
Absolutely.
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The donation goes directly to the neuropathology research laboratory.
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Yes. Just reach out and we can share opportunities.
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Yep.
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Yes you can.