CRARY LAB
Every brain that arrives at our laboratory tells a story—carrying within it the molecular events that led to disease and the potential keys to prevention. We believe the answers to neurodegenerative diseases live in human tissue, not just animal models or cell cultures that merely reflect shadows of the true disease process. Our research focuses on unraveling the molecular changes in tauopathies—a diverse family of brain diseases including Alzheimer's disease, Parkinsonsonism, and chronic traumatic encephalopathy—using an interdisciplinary approach that combines traditional neuropathology with cutting-edge genetics, transcriptomics, and revolutionary artificial intelligence tools. We deploy these methods not just to catalog what went wrong, but to pinpoint the earliest triggers when prevention might still be possible, because we believe it's never too late for neuropathology when paired with modern technologies. Most importantly, we measure our success not only by what we discover, but by how generously we share tissues, data, and knowledge with the global research community, training the next generation of neuropathologists who will multiply our impact far beyond what any single laboratory could achieve. Behind every breakthrough is a patient who chose to contribute their final gift to science and a family who trusted us to honor their loved one's legacy by turning tragedy into hope for countless others.
CONFERENCES
Clinical Neuropathology &
Diagnostic biomarkers
Digital Pathology & AI