The Crary laboratory is located at the Icahn School of Medicine at Mount Sinai, on the upper east side of the borough of Manhattan in New York City. The ISMMS received $318.4 million in National Institutes of Health (NIH) funding awarded in 2017 making it 13th among U.S. medical schools and is 1st in research dollars per principal investigator among U.S. medical schools by the Association of American Medical Colleges (AAMC). The ISMMS has 36 multidisciplinary research, educational, and clinical institutes and 33 academic departments, with an annual budget of $2.7 billion. There are more than 6,369 full-time, part-time, and voluntary faculty. The ISMMS was named 4th among “World’s Most Innovative Companies in Data Science” by Fast Company magazine in 2016.
The Crary laboratory consists of approximately 1200 sq ft. of space in a 3000 sq. ft open-plan multi-investigator laboratory on the 9th floor of the Icahn Building at Mount Sinai School of Medicine. The laboratory is equipped for a wide range of histopathological studies of post-mortem brain tissue, including histology and staining equipment (e.g., tissue processors, embedders, microtomes, etc). The laboratory is also has a Ventana BenchMark XT automated IHC/ISH slide staining system. The laboratory is also equipped for biochemical, cell and molecular studies, with refrigerators, freezers, microwaves, gel electrophoresis equipment, microfuges, QPCR machines, water baths, laminar flow hoods, etc. The lab also has a KingFisher™ Flex Purification System for DNA and RNA isolation.
We are currently seeking a motivated and passionate individual to work on neurodegenerative tauopathies, including Alzheimer's disease, primary age-related tauopathy, and chronic traumatic encephalopathy. The candidate will join out highly active research program within the Mount Sinai Alzheimer’s disease research center and the Ronald M. Loeb Center for Alzheimer’s disease. Interested individuals will be encouraged to develop an independent research program and eventually apply for independent grant funding. The applicant should have experience with common molecular and cellular biology techniques (e.g., immunoblotting, cell culture, viral and plasmid vectors, PCR, QPCR, tissue sectioning, immunohistochemistry, in situ hybridization and fluorescence microscopy). Additional skills that are valued include: 1. RNA biology 2. Neurogenetics 3. Cell culture 4. Bioinformatics 5. Neuropathology 6. Stereology Please send a C.V. and the names of at least two references to John Crary (firstname.lastname@example.org).
We currently have a position open for a graduate student. Please contact Dr. Crary for more information.
The laboratory takes one to two masters students per year and we currently have an opening. Please contact Dr. Crary for more information.
We are always seeking highly motivated assistants for the neuropathology brain bank. Volunteers will learn the basics of neuroanatomy and diagnostic neuropathology. Volunteers will gain exposure to challenges associated with treating, diagnosing, and studying brain diseases. Volunteers will have the opportunity to finish this program after 1 semester and become paid assistant prosectors. Responsibilities include: Assisting physicians (prosectors) and assistant prosectors in brain dissection and processing of brain tissue, interfacing with neuropathologists and research scientists, attendance and participation in brain bank meetings, presenting on a neuropathology-related topic at one brain bank meeting, annotate digital images of sectioned brain slabs (identify and label relevant neuroanatomical regions of interest. Requirements: Post graduate (postbacc student), Strong academic performance (e.g. recommended 3.3 GPA minimum in a scientific discipline), Some exposure to neuroscience (i.e. undergraduate major), psychology, or related discipline, excellent organizational skills, excellent interpersonal and communication skills, intent to matriculate into an M.D. or M.D.- Ph.D. program at the conclusion. Time commitment is 2 days per week - 5 hours 1 day a week (~12-5pm) (during the week you will be on call), 4.5 hours on Fridays (10:30-3 pm), and 1 weekend per month. Hours are flexible. To apply, please email your resume and cover letter to both email@example.com and firstname.lastname@example.org